PRODUCT DESCRIPTION

[Lysis Timer] is a semi-automated device for the study of euglobulin lysis time (or analysis of clot dissolution kinetics resulting from thrombin coagulation) in a sample of citrated human plasma in the presence of human tPA (recombinant) and silica (tPA-silica solution). It is a measuring device for professional use in a laboratory or similar environment for research purposes only.

It measures the turbidity of the medium photometrically on each of its 8 measuring channels heated to 37°C.

This quantitative test aims to reproduce the manual method of Von Kaulla to obtain comparable results. It consists of introducing into a tube a micro-volume of citrated plasma incubated at 37°C into which a specific reagent is injected before starting the measurement. During the measurement, the sample is crossed by an infrared beam while being maintained at a temperature of 37°C and the instrument records the evolution of the clot from its formation to its destruction.

The dedicated software [LysisControl] installed on a PC and connected to the instrument, allows to control the 8 measurement channels, to record the sample and test data, to plot the measurement curves, to perform the calculations and to save the results.

The Lysis Timer (LT) is a handheld device, optimized by HYPHEN BioMed to evaluate Global Fibrinolytic Capacity (GFC) in citrated plasma.

PRODUCT CHARACTERISTICS

PRODUCT COMPONENTS

Measuring channels: 8

Temperature control: Measuring channels heated to 37°C ± 1°C

Duration of temperature rise and control: 20 minutes

Protocol: Measurement of euglobulin lysis time / Analysis of clot dissolution kinetics

Primary sample: human blood collected onto the trisodium citrate anticoagulant

Sample volume (per test): 100µL

Reagents: CK093K “GFC-Test” HYPHEN BioMed:

• R1: tPA with Silica
• R2: Thrombin

Test preparation:

• introduce in a cuvette at 37°C:
• 100µL citrated plasma (Samples are tested undiluted)
• 100µL CK093K (R1 tPA with silica, homogenized before use)
• Mix and incubate at 37°C, for about 1 minute then introduce:
• 100µL CK093K (R2 Thrombin)
• Mix by vortexing.

Measurement principle: Turbidity measurement

Measuring method: Photometric method

Dimensions: Height = 75mm; Width = 60mm; Depth = 175mm

Weight: 1.1kg

Electrical specifications instrument (input):

• DC voltage: 12V
• Rated current: 3.33A
• Power rating (max.): 40W

Electrical specifications AC power adapter:

• Adapter with EU plug :
• Input: 100-240VAC +- 10%, 50/60Hz, 0.9-0.45A
• Output: 12V (direct current) 3A, 36W MAX
• NOTE: This accessory is included with the purchase of the Lysis Timer

Connections : USB port + Power adapter

Communication cable: USB cable

Temperature limits (operation / storage): [19 – 30°C] / [0 – 40°C]

Humidity limits (operation / storage): [20% – 80%] RH non-condensing / [10% – 80%] RH

Operating environment:

• < 2000meter
• pollution degree 2

Computer requirements (minimum): Microsoft Windows 10 ®; Processor 1.5GHz; HDD 60GB; pdf reader

Data processing functions: Controlling measurement channels, recording sample and test data, plotting measurement curves, performing calculations, and saving results

Maintenance and cleaning: Cleaning with a non-corrosive disinfectant

PRODUCT APPLICATION